Bioactive Small Molecules
Medchemexpress LLC (E)-N-(4-(1-(3-Aminobenzoyl)piperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide | 2222981-61-3 | 99.6% | 406.52 | 50 MG
Nampt-IN-15 is an Nampt inhibitor. It demonstrates cytotoxicity against BxPC-3, HepG2, L540cy, and MOLM-13 cell lines, with IC50 values of 38.5 nM, 8 nM, 8.5 nM, and 7 nM respectively. It is intended for research use only.
- Nampt inhibitor.
- Shows cytotoxicity against various cell lines: BxPC-3 (IC50: 38.5 nM), HepG2 (IC50: 8 nM), L540cy (IC50: 8.5 nM), and MOLM-13 (IC50: 7 nM).
Medchemexpress LLC Florfenicol | 73231-34-2 | 99.7% | 25 MG
Florfenicol (Standard) is an analytical standard of Florfenicol, an orally active broad-spectrum antibacterial antibiotic. It exhibits anti-inflammatory, pro-apoptotic, and immunomodulatory functions, making it suitable for research and analytical applications.
- Used in qualitative, quantitative, and methodological research experiments
- Applicable in HPLC, GC, and MS
- Suitable for laboratory chemical uses and substance manufacturing
- Intended for research use only
Medchemexpress LLC Palbociclib impurity 1 | 1884279-18-8 | MFCD30741324 | 5mg
Palbociclib impurity 46 is an impurity of Palbociclib (HY-50767)
Medchemexpress LLC HY-B1390B 500mg Medchemexpress, Saccharin (sodium hydrate) CAS:82385-42-0 Purity:>98%
Medchemexpress, HY-B1390B 500mg Saccharin (sodium hydrate) CAS:82385-42-0 Saccharin sodium hydrate is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium hydrate has bacteriostatic and microbiome-modulating properties. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N1513 5mg Medchemexpress, Ganoderic acid H CAS:98665-19-1 Purity:>98%
Medchemexpress, HY-N1513 5mg Ganoderic acid H CAS:98665-19-1 Ganoderic acid H is a lanostane-type triterpene isolated from Ganoderma lucidum. Ganoderic acid H suppresses growth and invasive behavior of breast cancer cells through the inhibition of transcription factors AP-1 and NF-kappaB signaling. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Tamra azide, isomer 5 | 1006592-61-5 | 99.0% | 554.64 g/mol | C31H34N6O4 | 10mg
Tamra azide is a red fluorescent probe The azide group of Tamra azide can react with alkynes via copper-catalyzed click chemistry[1]
Medchemexpress LLC KVA-D-88 | 2410550-31-9 | 99.8% | 382.19 | 1 ML
KVA-D-88 is a blood-brain barrier-permeable PDE4 inhibitor with IC50 values of 140 and 880 nM for PDE4B and PDE4D, respectively. It inhibits cocaine-induced hyperlocomotor activity and sensitization, selectively inhibiting PDE4B and reducing cAMP degradation, thereby modulating neuroadaptive responses. It can be used in the study of cocaine addiction.
- Blood-brain barrier-permeable PDE4 inhibitor
- Inhibits cocaine-induced hyperlocomotor activity and sensitization
- Selectively inhibits PDE4B and reduces cAMP degradation
- Modulates neuroadaptive responses
- Useful in the study of cocaine addiction
eMolecules 2641993-55-5 | Medchem Express | RM-018 | 5mg | 713706632 | HY-141477 | 985.24 | C56H72N8O8
Medchem Express | ONO-7300243 | 5mg | 446256258 | HY-100882 | 638132-34-0 | MFCD30534399 | 461.558 | C28H31NO5
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TARGETMOL CHEMICALS INC DB1976 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. DB1976 is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 potently inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-(lambda)B affinity KD of 12 nM) in vitro. DB1976 has Apoptosis-inducing effect. purity: 98%
Medchemexpress LLC Bamaquimast | 135779-82-7 | MFCD00904310 | 98.97% | 303.36 g/mol | C16H21N3O3 | 1 ML
Bamaquimast is a research reagent described as a potent antiasthmatic agent. Supplied as a ready-to-use 10 mM solution in DMSO for laboratory research, it is intended for experimental studies; consult safety documentation and handling instructions before use.
- Ready-to-use 10 mM solution in DMSO.
- Supplied as a 1 mL aliquot.
- High purity (98.97%).
- Molecular weight 303.36 g/mol; formula C16H21N3O3.
- CAS number 135779-82-7.
- For research use only; not for human or clinical use.
eMolecules 2086301-47-3 | Medchem Express | (SRS)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH | 10mg | 633697026 | HY-131168 | 1509.98 | C78H116N12O14S2
ChemScene | 5-Bromo-13-dihydrobenzoimidazol-2-one | 1g | 491371333 | CS-W005438 | 39513-26-3 | MFCD28947289 | 213.034 | C7H5BrN2O
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Medchemexpress LLC Echitamine chloride | 6878-36-0 | 1 MG
Echitamine chloride, also known as Ditaine chloride, is a prominent monoterpene indole alkaloid found in Alstonia scholaris. It is known for its potent anti-tumour properties, operating by inducing DNA fragmentation and promoting cell apoptosis. Additionally, it acts as an inhibitor of pancreatic lipase.
- Potent anti-tumor activity
- Induces DNA fragmentation
- Promotes cell apoptosis
- Inhibits pancreatic lipase with an IC50 of 10.92 μM
Medchemexpress LLC Diiodohydroxyquinoline | 83-73-8 | 98.0% | 1 ML
Diiodohydroxyquinoline (Iodoquinol) is a compound with orally active antiparasitic properties. It exhibits potent anti-SARS-CoV-2 activity with an EC50 value of 1.38 μM in VeroE6 cells, and its antimutagen is ascorbic acid. This compound shows promise for research in inflammation, intestinal amebiasis, amebic liver abscess, and chronic nonspecific diarrheas.
- Possesses orally active antiparasitic properties.
- Exhibits mutagenic potential in mice.
- Shows potent anti-SARS-CoV-2 activity with an EC50 of 1.38 μM in VeroE6 cells.
- Antimutagen is ascorbic acid.
- Useful for research in inflammation.
- Useful for research in intestinal amebiasis.
- Useful for research in amebic liver abscess.
- Useful for research in chronic nonspecific diarrheas.
Medchemexpress LLC Thalidomide-Piperazine-PEG1-NH2 (diTFA) | 657.52 | 100 MG
Thalidomide-Piperazine-PEG1-NH2 (diTFA) is a chemical compound primarily intended for laboratory research and the manufacture of various substances. Presented as a solid, this product has a molecular weight of 657.52. It is designed for experienced personnel and research applications only, and has not been fully validated for medical uses. Proper storage is crucial: the recommended temperature is 4°C in sealed containers away from moisture. If stored in solvent, it can be kept at -80°C for 6 months or -20°C for 1 month, also in sealed conditions away from moisture.
- Designed for laboratory research applications
- Suitable for experienced personnel
- Molecular weight of 657.52
- Appears as a solid
- Store at 4°C, sealed, away from moisture
- In solvent, store at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC BMS-5 | 1338247-35-0 | 431.29 | 1 ML
BMS-5 (LIMKi 3) is a potent LIM kinase (LIMK) inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively. This compound is used in cancer research and inhibits cofilin-Ser3 phosphorylation in a dose-dependent manner.
- Potent LIM kinase inhibitor
- IC50 of 7 nM for LIMK1
- IC50 of 8 nM for LIMK2
- Target: LIM Kinase
- Research area: Cancer
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 2 years, -20°C for 1 year
- Solubility in DMSO: 100 mg/mL
- Reduces Nf2∆Ex2 MSC viability